Highlights

Automation and Data Science for Organometallic Reactions and Catalysis

Topical Reviews

Pd-Catalyzed Cross-Couplings: On the Importance of the Catalyst Quantity Descriptors, mol % and ppm
Catalytic C–H bond functionalisation chemistry: the case for quasi-heterogeneous catalysis
Emergence of PdIV Chemistry in Synthesis and Catalysis

MnI carbonyl catalysis and C-H bond activation

Direct Observation of the Microscopic Reverse of the Ubiquitous Concerted Metalation Deprotonation Step in C–H Bond Activation Catalysis
Light- and Manganese-Initiated Borylation of Aryl Diazonium Salts: Mechanistic Insight on the Ultrafast Time-Scale Revealed by Time-Resolved Spectroscopic Analysis
Mechanistic Insight into Catalytic Redox-Neutral C–H Bond Activation Involving MnI Carbonyls: Catalyst Activation, Turnover, and Deactivation Pathways Reveal an Intricate Network of Steps
Delineating the critical role of acid additives in Mn-catalysed C–H bond functionalisation processes
Mapping out the key carbon–carbon bond-forming steps in Mn-catalysed C–H functionalization
MnI-Catalyzed C−H Activation: The Key Role of a 7-Membered Manganacycle in H-Transfer and Reductive Elimination

Cross-coupling, C-H activation: Involvement of Pd3 clusters and Pd nanoparticles

Pd-Catalysed carbonylative Suzuki–Miyaura cross-couplings using Fe(CO)5 under mild conditions: generation of a highly active, recyclable and scalable ‘Pd–Fe’ nanocatalyst
The ubiquitous cross-coupling catalyst system ‘Pd(OAc)2’/2PPh3 forms a unique dinuclear PdI complex: an important entry point into catalytically competent cyclic Pd3 clusters
Catalytic C–H bond functionalisation chemistry: the case for quasi-heterogeneous catalysis
Evidence for the Surface-Catalyzed Suzuki–Miyaura Reaction over Palladium Nanoparticles: An Operando XAS Study

On impurities in Pd(OAc)2/nitrite linkage isomerisation at Pd and Pd-NOx redox activity in C-H bond activation

Redox Couple Involving NOx in Aerobic Pd-Catalyzed Oxidation of sp3-C–H Bonds: Direct Evidence for Pd–NO3–/NO2– Interactions Involved in Oxidation and Reductive Elimination
Redox-Active NOx Ligands in Palladium-Mediated Processes
On the appearance of nitrite anion in [PdX(OAc)L2] and [Pd(X)(C^N)L] syntheses (X = OAc or NO2): photocrystallographic identification of metastable Pd(η1-ONO)(C^N)PPh3

Catalysis with Au-NHC, Au-NHC nanoparticles; Cu-NHC complexes and C-H bond functionalization

Theoretical rationalisation for the mechanism of N-heterocyclic carbene-halide reductive elimination at CuIII, AgIII and AuIII
N-Heterocyclic carbene coated metal nanoparticles
Pd0/CuI-Mediated Direct Arylation of 2′-Deoxyadenosines: Mechanistic Role of CuI and Reactivity Comparisons with Related Purine Nucleosides

Total synthesis of phacelocarpus 2-pyrone A – application of AsCat, imidate ligand effects

Total Synthesis and Stereochemical Revision of Phacelocarpus 2-Pyrone A
AsCat and FurCat: new Pd catalysts for selective room-temperature Stille cross-couplings of benzyl chlorides with organostannanes

Biocatalysts for the synthesis of pharamceutically-relevant amides

The Broad Aryl Acid Specificity of the Amide Bond Synthetase McbA Suggests Potential for the Biocatalytic Synthesis of Amides
Biocatalytic Synthesis of Moclobemide Using the Amide Bond Synthetase McbA Coupled with an ATP Recycling System

π-Acidic alkene ligand effects at Pd, including dibenzylidene acetone (dba) ligands

The Elusive Structure of Pd2(dba)3. Examination by Isotopic Labeling, NMR Spectroscopy, and X-ray Diffraction Analysis: Synthesis and Characterization of Pd2(dba-Z)3 Complexes

C-H bond activation in tryptophan containing compounds and aryl/heteroaryl diazonium salts

A Need for Caution in the Preparation and Application of Synthetically Versatile Aryl Diazonium Tetrafluoroborate Salts
Mild and Regioselective Pd(OAc)2-Catalyzed C–H Arylation of Tryptophans by [ArN2]X, Promoted by Tosic Acid
A mild and selective Pd-mediated methodology for the synthesis of highly fluorescent 2-arylated tryptophans and tryptophan-containing peptides: a catalytic role for Pd0 nanoparticles?

Pericyclic processes, 6π-electrocylization and Pauson-Khand chemistry

Photochemical-mediated solid-state [2+2]-cycloaddition reactions of an unsymmetrical dibenzylidene acetone (monothiophos-dba)
Regiochemistry in Cobalt-Mediated Intermolecular Pauson–Khand Reactions of Unsymmetrical Internal Heteroaromatic Alkynes with Norbornene
A natural light induced regioselective 6π-electrocyclisation–oxidative aromatisation reaction: experimental and theoretical insights