Publications: 2000 – 2004

Below is a list of all publications from 2000 through to 2004. Each paper title, reference and DOI number are provided for ease of viewing.

2004
Palladacyclopentadiene complexes with mono- and didentate imidato ligands: Synthesis, hemilabile behaviour and catalytic application in the Stille reaction

Serrano J. L., Fairlamb I. J. S., Sanchez G., Garcia L., Perez J., Vives J., Lopez G., Crawforth C. M., Taylor R. J. K., Euro. J. Inorg. Chem., 2004, 2706

DOI: 10.1002/ejic.200300962


Important consequences for gas chromatographic analysis of the Sonogashira cross-coupling reaction

Serrano J. L., Fairlamb I. J. S., Sanchez G., Garcia L., Perez J., Vives J., Lopez G., Crawforth C. M., Taylor R. J. K., Euro. J. Inorg. Chem., 2004, 2706

DOI: 10.1016/j.tetlet.2004.03.060


Coordination of the Trost modular ligand to palladium allyl fragments: Oligomers, monomers, and memory effects in catalysis

Lloyd-Jones G. C., Stephen S. C., Fairlamb I. J. S., Martorell A., Dominguez B., Tomlin P. M., Murray M., Fernandez J. M., Jeffery J. C., Riis-Johannessen T., Guerziz T., Pure and Applied Chem., 2004, 76(3), 589

DOI: 10.1351/pac200476030589


2-Pyrones possessing antimicrobial and cytotoxic activities

Fairlamb, I. J. S., Marrison L. R., Dickinson J. M., Lu F. J., Schmidt J. P., Bioorg., Med. Chem., 2004, 12(15), 4285

DOI: 10.1016/j.bmc.2004.01.051


η1-Bound 2-pyrone complexes of molybdenum and iron: A synthetic and structural study

Fairlamb I. J. S., Lloyd-Jones G. C., Martorell A., Murray M., Stephen S. C., Tomlin P. M., Phosphorus, Sulfur and Silicon, 2004,149(4-5), 907

DOI: 10.1080/10426500490428889


Bis(triphenylphosphine)palladiumIIsuccinimide as a precatalyst for Suzuki cross-coupling-subtle effects exerted by the succinimide ligand

Fairlamb I. J. S., Kapdi A. R., Lynam J. M., Taylor R. J. K., Whitwood A. C., Tetrahedron, 2004, 60(27), 5711

DOI: 10.1016/j.tet.2004.05.018


Mono- and binuclear cyclometallated palladiumII complexes containing bridging (N,O-) and terminal (N-) imidate ligands: Air stable, thermally robust and recyclable catalysts for cross-coupling processes

Fairlamb I. J. S., Kapdi A. R., Lee A. F., Sanchez G., Lopez G., Serrano J. L., Garcia L., Perez J., Perez E., Dalton Transactions, 2004, 3970

DOI: 10.1039/b413886d


η2-dba complexes of Pd0: The substituent effect in Suzuki-Miyaura coupling

Fairlamb I. J. S., Kapdi A. R., Lee A. F., Org. Lett., 2004, 6(24), 4435

DOI: 10.1021/ol048413i


A one-pot remote allylic hydroxylation and Baeyer-Villiger oxidation of a bicyclo 3.2.0 hept-2-en-6-one by Cunninghamella echinulata NRRL 3655

Fairlamb I. J. S., Grant S., Grogan G., Maddrell D. A., Nichols J. C., Org. Biomol. Chem., 2004, 2(13), 1831

DOI: 10.1039/b406016d


Synthesis of jaspaquinol and effect on viability of normal and malignant bladder epithelial cell lines

Demotie A., Fairlamb I. J. S., Lu F. J., Shaw N. J., Spencer P. A., Southgate J., Bioorg. Med. Chem. Lett., 2004, 14(11), 2883

DOI: 10.1016/j.bmcl.2004.03.055


Efficient and selective Stille cross-coupling of benzylic and allylic bromides using bromobis(triphenylphosphine) (N-succinimide)palladiumII

C. M. Crawforth, I. J. S. Fairlamb, R. J. K. Taylor, Tetrahedron Lett., 2004, 45(3), 461

DOI: 10.1016/j.tetlet.2003.11.014


Bis(triphenylphosphine)palladiumIIphthalimide – an easily prepared precatalyst for efficient Suzuki-Miyaura coupling of aryl bromides

Chaignon N. M., Fairlamb I. J. S., Kapdi A. R., Taylor R. J. K., Whitwood A. C., J. Mol. Catal. A – Chemical, 2004, 219(2), 191

DOI: 10.1016/j.molcata.2004.05.008


A new precatalyst for the Suzuki reaction – a pyridyl-bridged dinuclear palladium complex as a source of mono-ligated palladium0

Beeby A., Bettington S., Fairlamb I. J. S., Goeta A. E., Kapdi A. R., Niemela E. H., Thompson A. L., New J. Chem., 2004, 28(5), 600

DOI: 10.1039/b401077a

2003
Suzuki cross-coupling approaches to the synthesis of bioactive 3-substituted and 5-substituted-4-methoxy-6-methyl-2-pyrones

Marrison, L. R., Dickinson, J. M., Fairlamb, I. J. S., Bioorg. Med. Chem. Lett., 2003, 13(16), 2667

DOI: 10.1016/s0960-894x(03)00546-8


Synthesis of (Bromo-η4-2-pyrone)tricarbonyliron complexes

Fairlamb, I. J. S., Syvanne, S. M., Whitwood, A. C., Synlett, 2003, 1693

DOI: 10.1055/s-2003-41428


Palladium-catalysed alkynylations of 2-pyrone (pyran-2-one) halides

Fairlamb I. J. S., Lu F. J., Schmidt J. P., Synthesis-Stuttgart, 2003, 2564

DOI: 10.1055/s-2003-42405


Synthesis and antimicrobial evaluation of farnesyl diphosphate mimetics

Fairlamb I. J. S., Dickinson J. M., O’Connor R., Cohen L. H., van Thiel C. F., Bioorg. Chem., 2003, 31(1), 80

DOI: 10.1016/s0045-2068(03)00025-7


Pd-catalysed cross coupling of terminal alkynes to diynes in the absence of a stoichiometric additive

Fairlamb I. J. S., Bauerlein P. S., Marrison L. R., Dickinson J. M., Chem. Commun., 2003, 632

DOI: 10.1039/b212430k


On the selective reduction of the distal olefin in geraniol and farnesol derivatives

Demotie A., Fairlamb I. J. S., Radford S. K., Tetrahedron Lett., 2003, 44(24), 4539

DOI: 10.1016/s0040-4039(03)01047-5


Bromobis(triphenylphosphine)(N-succinimide)palladiumII as a novel catalyst for Stille cross-coupling reactions

Crawforth C. M., Burling S., Fairlamb I. J. S., Taylor R. J. K., Whitwood A. C., Chem. Commun., 2003, 2194

DOI: 10.1039/b304960d

2002
Bioactive 4-substituted-6-methyl-2-pyrones with promising cytotoxicity against A2780 and K562 cell lines

Marrison L. R., Dickinson J. M., Fairlamb I. J. S., Bioorg. Med. Chem. Lett., 2002, 12(24), 3509

DOI: 10.1016/s0960-894x(02)00824-7


An efficient synthesis of 4-alkenyl/alkynyl-6-methyl-2-pyrones via Pd-catalysed coupling on 4-bromo-6-methyl-2-pyrone

Marrison L. R., Dickinson J. M., Ahmed R., Fairlamb I. J. S., Tetrahedron Lett., 2002, 43(49), 8853

DOI: 10.1016/s0040-4039(02)02207-4


Cycloisomerisation of Modified Terpenoid 1,6-enynes – Synthesis of Conformationally-Restricted Cyclic Farnesyl Analogues

Fairlamb I. J. S., Pike A. C., Ribrioux, S. P. C. P., Tetrahedron Lett., 2002, 43(30), 5327

DOI: 10.1016/s0040-4039(02)01003-1


Analysis of Stereochemical Convergence in Asymmetric Pd-Catalysed Allylic Alkylation Reactions Complicated by Halide and Memory Effects

Fairlamb I. J. S., Lloyd-Jones G. C., Stepan V., Kocovsky P., Chemistry – a European Journal, 2002, 8 (19), 4443

DOI: 10.1002/1521-3765(20021004)8:193.0.Co;2-3


Identification of Novel Mammalian Squalene Synthase Inhibitors Using a Three-Dimensional Pharmacophore

Fairlamb I. J. S., Dickinson J. M., O’Connor R., Higson S., Grieveson L., Marin V., Bioorg. Med. Chem., 2002, 10, 2641

DOI: 10.1016/s0968-0896(02)00090-1


Convenient, Rapid and Highly Regioselective Cycloisomerisation of 4,4′-disubstituted hepta-1,6-dienes Employing Neutral Palladium Chloride Pro-catalysts

Bray K. L., Fairlamb I. J. S., Kaiser J. P., Lloyd-Jones G. C., Slatford P. A., Top. Catal., 2002, 19, 49

DOI: 10.1023/a:1013881232382

2001
Structural and Mechanistic Studies on the Activation and Propagation of a Cationic Allylpalladium Procatalyst in 1,6-Diene Cycloisomerization

K. L. Bray, J. P. H. Charmant, I. J. S. Fairlamb, G. C. Lloyd-Jones

DOI: 10.1002/1521-3765(20011001)7:193.0.CO;2-Q


Selenium Dioxide E-Methyl Oxidation of Suitably Protected Geranyl Derivatives – Synthesis of Farnesyl Mimics

Fairlamb I. J. S., Dickinson J. M., Pegg M., Tetrahedron Lett., 2001, 42, 2205

DOI: 10.1016/s0040-4039(01)00110-1


Influence of PalladiumII Complexes on the Cycloaddition of Alpha-Bromoalkyl Ketenes to Cyclopentadiene

Fairlamb I. J. S., Dickinson J. M., Cristea I. M., Tetrahedron, 2001, 57, 2237

DOI: 10.1016/s0040-4020(01)00092-8


Halide Redistribution in Pd-Catalysed 1,6-diene Cycloisomerisation

Bray K. L., Fairlamb I. J. S., Lloyd-Jones G. C., Chem. Commun., 2001, 187

DOI: 10.1039/B009356O


Organometallic methods – stoichiometric transition metals

Lloyd-Jones G. C., Fairlamb I. J. S., Annu. Rep. Prog. Chem., Sect. B, 2001, 97, 113

DOI: 10.1039/b102848k

2000
On the effect of catalyst loading in Pd-catalysed allylic alkylation

Fairlamb I.J.S., Lloyd-Jones G.C., Chem. Commun., 2000, 2447

DOI: 10.1039/B007785M


Palladium-catalysed [π-2a+π-2s] cycloadditions of alpha-bromoalkyl ketenes to cyclopentadiene

Fairlamb I.J.S., Dickinson J.M., Cristea I.M., Tet. Lett., 2000, 41,3739

DOI: 10.1016/S0040-4039(00)00478-0